Inhibition of histone deacetylases (HDAC) has been evaluated as a potential therapeutic strategy for several protein folding and other chronic inflammatory diseases such as neurodegenerative diseases (Benito et al., 2015; Rabal et al., 2016), chronic kidney disease (Liu and Zhuang, 2015), inflammatory bowel disease (Felice et al., 2015), cancer (Falkenberg and Johnstone, 2014; West and Johnstone, 2014; De Souza and Chatterji, 2015), graft-versus-host disease (Choi et al., 2014, 2017), rheumatoid arthritis (Oh et al., 2017) and CF (Hutt et al., 2010, 2011; Bodas et al., 2018a). The gene discussed is HDAC9; the disease is cancer.