APOE and infection: Therefore, in summary, during EVD in rhesus macaques, Apo B100, ApoB48, and Apo E increase in expression and reach higher fold change values than the Bp-infected NHP, whereas Apo A1, Apo AII, Apo A4, Apo CIII and Apo H act as negative acute phase reactants in both infection types with comparable reductions.