RB1 and non-small cell lung carcinoma: In NSCLC, RB1 mutant status when compared to RB1 wt was associated with worse OS (8.3 months vs 28.3 months, Hazard Ratio (HR) = 2.59, 95% Confidence Interval (CI) = 1.4‐4.79, P = 0.002) and this was statistically significant (Figure 1).