In recent years, the Nrf2/HO‐1 system has been regarded not only as a modulator of aging and species longevity, but also as a promising therapeutic target in the vasculature to ameliorate pathologies such as restenosis, thrombosis, myocardial infarction, hypertension, or atherosclerosis (Durante, 2010). Here, HMOX1 is linked to atherosclerosis.