Xie J showed that the expression of miR‐374b‐5p was up‐regulated and conducive to gastric cancer cell invasion and metastasis via inhibiting the expression of RECK.24 Ji et al25 presented that the up‐regulation of miR‐374 mediated the malignant transformation of gastric cancer‐associated mesenchymal stem cells and represented a novel avenue for gastric cancer therapy with an experimental rat model. The gene discussed is RECK; the disease is gastric cancer.