Other common side effects include somnolence and general toxicity (all RLS medications); impulse control disorders (dopamine-receptor agonists); dyskinesias (dopaminergic agents), nausea and vomiting (dopaminergic agents, opioids); mood disturbances (α2δ ligands, opioids, benzodiazepines); weight gain (α2δ ligands); addiction (opioids, benzodiazepines); increased risk for falls (opioids, benzodiazepines), and other adverse sequelae [25, 26, 30, 31, 34, 36–44]. Here, ATXN2L is linked to Coma.