LEF1 and acute myeloid leukemia: Interestingly, despite strong correlation between LEF1 and LEF1‐AS1 expression (Supplementary), only LEF1‐AS1 expression was positively correlated with AML patient survival (LEF1‐AS1: P value (two‐tailed) = 0.0423 Pearson r = 0.3934, 95% confidence interval = 0.01567‐0.6729), Figure 1H. Supporting these results, normal haematopoietic stem cells (CD34+HSCs) express high levels of LEF1‐AS1 when compared to malignant cell lines and LEF1‐AS1 expression is particularly suppressed in myeloid malignant cells (Figure 2C).