CEACAM5 and cancer: Lastly, Yu et al. developed a capillary-based 3-D fluoro-immunosensor capable of detecting and quantifying the salivary levels of carcinoembryonic antigen which were involved in a wide array of cancers, with a limit of detection of 0.2 ng/mL and a relative mean recovery rate between 92.82% and 118.81% [59].