Stellettin B has been demonstrated to cause cell death through the inhibition of the PI3K/Akt/mTOR pathway, which generates reactive oxygen species in SF295 glioblastoma cells [5], and the induction of mitochondria-related apoptosis through the inhibition of K562 human chronic myeloid leukemia cells [7]. The gene discussed is AKT1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.