Furthermore, EMT is closely related to cancer metastasis, which can typically be characterized by different molecular markers.38, 39 In this study, treatment with rhCCL18 down‐regulated the expression of E‐cadherin, an epithelial cell marker, and up‐regulated expression of mesenchymal markers such as Vimentin, N‐cadherin and Fibronectin at mRNA level (Figure 3A). This evidence concerns the gene VIM and cancer.