Here we validated PLAIDOH’s functional predictions for RP11-960 L18.1, confirming that it is not a cis-regulatory lncRNA for PLCG2, but rather likely acts in the cytoplasm by interacting with one or more RBPs (NF90, KHDRBS1, PUM2) to promote the growth of lymphoma cells. The gene discussed is KHDRBS1; the disease is lymphoma.