CES2 and metabolic dysfunction-associated steatotic liver disease: Recently, two independent studies demonstrated that Ces2c/CES2 can act as a TGH and that reduced hepatic expression of Ces2c/CES2 is linked to NAFLD development in obese mice and humans.6, 7Ces2c is expressed in lipoprotein‐producing organs with highest expression levels in the duodenum.8 To examine the role of Ces2c in intestinal lipid metabolism, we generated and characterized mice overexpressing Ces2c in the intestine.