Among the most important findings from the mind–body literature is the observation that exposure to psychological stress significantly increases vulnerability to poor health outcomes across a wide variety of physical conditions (Cohen, Janicki-Deverts, & Miller, 2007; Morey, Boggero, Scott, & Segerstrom, 2015) For persons with type 1 diabetes (T1D), stress has the potential to affect metabolic control directly through its impact on cortisol and other catecholamine hormones that affect insulin metabolism (Helgeson, Siminerio, Escobar, & Becker, 2008). This evidence concerns the gene INS and type 1 diabetes mellitus.