MAPT and chronic obstructive pulmonary disease: In fact, D. melanogaster has been used to study pathologies related to brain function (A beta and tau pathology, Parkinson disease, Huntington disease) [19], respiratory function (asthma, chronic obstructive pulmonary disease (COPD)) [20, 21], motoric function (muscular dystrophy, amylotrophic lateral sclerosis) [22]), renal function (nephtrolithiasis) [23], gut disorders [24], diabetes [25], and heart function (cardiomyopathy) [26] as well as psychiatric disorders (ADHD, alcohol, and other addictions) [27, 28].