It has been reported that α-GalCer stimulation can induce iNKT cells to produce both anti-inflammatory cytokines (e.g., IL4, IL13, and IL10) and pro-inflammatory cytokines (e.g., IFNγ, TNFα, and IL17), ultimately determining the outcome of autoimmune diseases such as EAE [32]. The gene discussed is IL17A; the disease is autoimmune disease.