We also found that the treatment of established MGH-U3 xenografts in nude mice with intraperitoneal injections of TYRO3 siRNA reduced significantly the tumour growth as compared to in similar tumours treated with a scramble siRNA (≈354 mm3 versus 1090 mm3 at day 21, p < 0.0001) (Fig. 3b). Here, TYRO3 is linked to neoplasm.