TGFB1 and neoplasm: The top 10 KEGG pathways in the dysregulated mRNAs are shown in Fig. 6c, including “cell adhesion molecule,” “cytokine-cytokine receptor interaction,” “ECM receptor interaction,” and “TGF-β signaling pathway.” Thus, we hypothesized that ADQ contributes to the inhibition of aggressive tumor behavior by inactivating cell adhesion molecules and the epithelial-to-mesenchymal transition (EMT), suggesting a tight link between ADQ and biological processes involving tumor migration and metastasis.