Treatment with either inhibitor prior to infection led to a significant reduction in the secretion of all cytokines and chemokines examined, including CXCL8, growth-related oncogene-α (GRO-α), granulocyte colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF), all of which have important roles in neutrophilia [27]. Here, CSF3 is linked to infection.