Treatment with either inhibitor prior to infection led to a significant reduction in the secretion of all cytokines and chemokines examined, including CXCL8, growth-related oncogene-α (GRO-α), granulocyte colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF), all of which have important roles in neutrophilia [27]. This evidence concerns the gene CSF2 and infection.