The pooled survival results of Plexin-B1, SEMA4D high affinity receptor, precisely remedied the insufficient in breast cancer studies: Plexin-B1 level showed a significant positive correlation both with OS and DFS (respectively, HRos = 0.56, 95%CI: 0.39–0.79, P = .001; HRdfs = 0.68, 95%CI = 0.51–0.90, P = .008). Here, SEMA4D is linked to breast carcinoma.