In this study, we aimed to determine (i) whether a correlation exists between fetuin-A and hs-CRP levels, nutritional parameters, carotid intima-media thickness (CIMT) or vascular calcification scores (VCS) in stage-3, stage-4, and ESRD patients, (ii) whether fetuin-A, hs-CRP levels, nutritional parameters, CIMT, and VCS are different in patients with stage-3 and stage-4 CKD compared to patients with ESRD. This evidence concerns the gene AHSG and chronic kidney disease.