The Glut-1 isoform is overexpressed in a variety of malignant neoplasms, including brain, hepatic, and pancreatic tumors (Shibuya et al., 2015; Barron et al., 2016) and correlates with tumor aggressiveness and poor prognosis (Kunkel et al., 2003). The gene discussed is SLC2A1; the disease is cancer.