CDKN2B antisense RNA 1 (CDKN2B-AS) gene is a lncRNA gene identified by Pasmant et al. during the genetic study of a melanoma-neural system tumor family in 2007, that also named Antisense Non-coding RNA In The INK4 Locus (ANRIL) (13). The gene discussed is CDKN2B-AS1; the disease is melanoma.