We have previously shown a relation between inflammatory cytokines and expression of JE‐specific genes, such as amelotin (AMTN) 5, 6, 7, 8, odontogenic ameloblast‐associated protein (ODAM) and follicular dendritic cell‐secreted protein (FDC‐SP) 9, 10, 11, during dental development and regeneration of JE in gingival epithelial cells and a Porphyromonas gingivalis (Pg)‐ and Aggregatibacter actinomycetemcomitans‐infected mouse periodontitis model 12. This evidence concerns the gene AMTN and periodontitis.