While TRPV3 was not detectable in any of these 3 cell lines, which was consistent with the result of the mRNA experiments (Fig. 1A), it should be noted that TRPV‐1, 2, and 4 were found to be upregulated among the ESCC cells compared with the nontumor esophageal squamous cells (Fig. 1B,C), implying that they may involve in the pathology of ESCC. Here, TRPV1 is linked to esophageal squamous cell carcinoma.