TRPV4 and esophageal squamous cell carcinoma: Previous in vivo work reported that sensory neurons did not exhibit osmosensitive inward currents and the activation of peripheral osmoreceptors was abolished by knockout of TRPV4 62, revealing that TRPV4 is the key channel responding to osmotic stimuli, thus further supporting the notion that overactivation of TRPV4 plays a pro‐migration role in ESCC cells.