Another promising marker is the TMPRSS2-ERG fusion (Tomlins et al., 2005; Rubin et al., 2011), which is specific for PCa and can even be detected in precursor lesions such as prostate intraepithelial neoplasia (Mehra et al., 2008; Han et al., 2009). This evidence concerns the gene ERG and posterior cortical atrophy.