AKT1 and glioblastoma: Moreover, has-miR-124-3p overexpression expressively inhibits GBM cell proliferation, migration, and tumor angiogenesis, which results in cell cycle arrest and GBM apoptosis putatively via the activation of the NRP-1-mediated PI3K/Akt/NFκB pathway in GBM cells, as well as suppressing tumor growth and reducing tumor angiogenesis (Zhang G. et al., 2018).