FCGR3B CNV has been shown to affect various diseases, i.e., a low CNV of FCGR3B was shown to result in an increased susceptibility to autoimmune diseases like systemic lupus erythematosus (SLE) (11, 12), primary Sjogren's syndrome (pSS) (12), Wegener's granulomatosis (WG) (12) and rheumatoid arthritis (RA) (13). The gene discussed is FCGR3B; the disease is granulomatosis with polyangiitis.