Interestingly, increases in small intestinal T cell numbers following ileitis induction were paralleled by elevated numbers of FOXP3+ cells in the ileal mucosa and lamina propria of both, Psae and mock challenged mice at day 9 p.i. (p < 0.001; Figure 5D; Supplemental Figure S3D) with higher counts in the former as compared to the latter (p < 0.001; Figure 5D; Supplemental Figure S3D). Here, FOXP3 is linked to Crohn ileitis.