High LAYN expression levels were associated with poorer prognosis of OS and DFS in COAD, OV (ovarian serous cystadenocarcinoma), and UVM (uveal melanoma); DFS in GBM (glioblastoma multiforme) and OS in HNSC, MESO (mesothelioma) and STAD. Here, LAYN is linked to gastric adenocarcinoma.