SIRT7 and colorectal cancer: SIRT7 was found overexpressed and upregulated in several tumors, including ovarian cancer (Wang et al., 2015), colorectal cancer, osteosarcoma (Wei et al., 2017), prostate cancer (Haider et al., 2017), breast cancer (Geng et al., 2015), and HCC (Kim et al., 2013).