SIRT1 expression is found increased in hematopoietic malignancies such as T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, diffuse large B-cell leukemia, and chronic myeloid leukemia (CML) (Jang et al., 2008; Wang et al., 2011; Kozako et al., 2012). The gene discussed is SIRT1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.