GJC2 and myeloid sarcoma: For instance, a murine model of MS-the experimental autoimmune encephalomyelitis (EAE; Constantinescu et al. (2011))-showed a reduction in GJ plaques composed by both Cx32 or Cx47 in oligodendrocytes within and around lesions but also in the normal appearing white matter (Markoullis et al., 2012).