Maintenance treatment includes retinoic acid aiming to differentiate the remaining tumor cells and immunotherapy using anti-GD2 together with granulocyte macrophage colony stimulating factor (GM-CSF) and interleukin-2 (IL-2; Yu et al., 2010; Ladenstein et al., 2013; Park et al., 2014; Matthay et al., 2016; Berlanga et al., 2017; Shohet and Foster, 2017). This evidence concerns the gene CSF2 and neoplasm.