ATRX and neuroblastoma: In addition, mutations in the histone acetyl transferase (HAC) genes EP300 and CREBBP, the SWI2/SNF2 family member TTF2 gene, the histone demethylase gene KDM5A, the chromatin remodeling zinc finger gene IKZF1 and ATRX, described above, has also been reported in neuroblastoma (Sausen et al., 2013).