Yew-Booth53 and colleagues have previously described an increase in STAT3 levels, but not phospoSTAT3 levels, in patients with COPD compared to smokers using imunohistochemsitry, whereas when the authors analyzed the levels of these cytokines using western blotting, they detected increased levels of both STAT3 and phosphoSTAT3. The gene discussed is STAT3; the disease is chronic obstructive pulmonary disease.