BRD4 and cancer: For example, the well-known oncogenic HAMP BRD4 was recurrently amplified in six cancer types, including adrenocortical carcinoma (ACC), breast invasive carcinoma (BRCA), ESCA, liver hepatocellular carcinoma, ovarian serous cystadenocarcinoma (OV), and uterine corpus endometrial carcinoma (UCEC) (Fig. 2b).