BRCA1 and coinfection: We found BRCA1 proteins were decreased after LV-210 infection compared with LV-CN infection, while BRCA1 proteins were increased after LV-210 and LV-BARD1 co-infection compared with LV-210 infection (Fig. 4c; Supplementary Figure 8, P < 0.05, paired Student's t-test), demonstrating that miR-210-3p suppresses BRCA1 expression by targeting BARD1.