IL1A and neoplasm: As the level of cytokines released by PDAC cells is relatively low (Additional file 4: Figure S4b-4c), we performed dose response curves and found that TSLP secretion was still detectable at concentrations usually present in tumor cell lysates and as low as 0.1 ng/ml for IL-1α and IL-1β, while TNF-α showed a statistically significant effect only down to 1 ng/ml (Fig. 1b).