Additionally, among the 12 over-edited sites in GBM, 10 sites showed a slight editing increase in GBM ranging from 1 to 5% Δ medians (Additional file 3: Table S2) and only 2 sites displayed an editing increase > 15% Δ medians in GBMs compared to the normal brain: COG3 I/V and CADPS E/G (both with Δ medians = 17%) (Additional file 3: Table S2). This evidence concerns the gene CADPS and glioblastoma.