However, the hub-genes, involved in CD19 (degree = 5), fibroblast growth factor 9 (FGF9; degree = 5), SRY (sex determining region Y)-box 9 (SOX9; degree = 5), guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1(GNGT1; degree = 4), and noggin (NOG; degree = 4), are demonstrated in stroke-DEGs with a relative higher degree. The gene discussed is NOG; the disease is stroke disorder.