SKP2 and breast cancer: SKP2 mRNA high expression was found to be correlated to significantly poor prognosis for breast cancer patients (Affymetrix ID: 203625_x_at, HR = 1.75 (1.57–1.96), p < 1e-16; Affymetrix ID: 203567_x_at, HR = 1.33 (1.19–1.49), p = 2.2e - 07) (Fig. 5c).