miR-155 upregulation correlated with an increased activation of macrophages, which lead to the overproduction of inflammatory cytokines and chemoattractants, such as interleukin-1β (IL-1β), TNF-α, and monocyte chemoattractant protein 1 (MCP-1) that further recruited more leukocytes to the ischemic heart [78]. Here, CCL2 is linked to benign neoplasm.