At start of GH treatment, GH dosage was comparable (0.23 ± 0.08 mg/kg/week versus 0.22 ± 0.07 mg/kg/week, p = 0.09), but after one year, GH dosage was higher in subjects with T1DM and GHD (0.24 ± 0.08 mg/kg/week versus 0.21 ± 0.07 mg/kg/week, p = 0.04). This evidence concerns the gene GH1 and type 1 diabetes mellitus.