For example, 50% of the ‘Gene: MLH1’ subpopulation had colorectal cancer before age 50 years, with a mean onset age at 44 ± 14.25 years (Figure 4C), compared to 0% of the ‘Gene: PMS2’ subpopulation that had colorectal cancer before age 50 years, with a mean onset age at 57 ± 4.36 years (Figure 4D). Here, PMS2 is linked to colorectal cancer.