Using sFlt‐1/PlGF ratio to predict the preeclampsia, when the area under ROC curve (AUC) was 0.918 (0.889‐0.946), the diagnostic sensitivity was 85.42%, the specificity was 96.27%, the positive predictive value was 89.1%, the negative predictive value was 94.9%, the positive likelihood ratio was 22.9, the negative likelihood ratio was 0.15, and the Youden index was 0.817 when cut‐off value was 26.6. This evidence concerns the gene PGF and preeclampsia.