For the up-regulated genes, MAGEA3 (t = 1.817, DF = 157, p = 0.071), MAGEA6 (t = 1.818, DF= 157, p = 0.071), and CSAG3 (t = 1.849, DF = 157, p = 0.066) were shown to have a higher trend (0.05 < p < 0.1) in HCC-A group than HCC-N group while CSMD1 and CSAG1 showed no significant expressional difference between the HCC-A group and other HCC groups. The gene discussed is CSAG3; the disease is hepatocellular carcinoma.