SPP2 and hepatocellular carcinoma: Comparing with other HCC groups, through independent samples T tests, IGF2 (t = −2.36, DF = 157, p = 0.02), SPP2 (equal variances not assumed, t = −3.030, DF = 45.723, p = 0.004), and SLC22A10 (t = −2.031, DF = 77, p = 0.046) were shown to be significantly lower in HCC-A than the HCC-N group, HCC-AC group, and the HCC-NAF group, respectively.