Specifically, its role in cell proliferation was supported by the observation that siRNA-mediated reduction of hnRNPA2B1 levels provoked rapid cell death by apoptosis in cell lines derived from diverse cancers of the cervix, colon, breast, ovary, and brain, but not in noncancerous fibroblastic or epithelial cell lines38. The gene discussed is HNRNPA2B1; the disease is cancer.