ITGAM and breast adenocarcinoma: Phenotypic analysis of MDSCs accumulated in the lungs of mice bearing mammary adenocarcinoma showed that CD11b+Gr-1+ MDSCs, but not CD11b+Gr-1− MDSCs and macrophages, are recruited in metastatic lungs, indicating that CD11b+Gr-1+ MDSCs are major, specific constituents which contribute to metastatic niche formation in the lungs [12].