Interleukin-1β (IL-1β) (4.617 [4.331, 4.921]), IL-6 (3.882 [3.270, 4.608]), IL-8 (3.679 [3.414, 3.964]), and Kerbs von Lungren-6 (KL-6) (3.178 [2.931, 3.446]) ranked the highest in biomarkers associated with ARDS mortality. This evidence concerns the gene IL1B and acute respiratory distress syndrome.