In our meta-analysis, biomarkers for ARDS diagnosis were related to inflammation (IL-8 and IL-6), endothelial injury (SICAM), epithelial injury (SRAGE and HGF), lung fibroproliferation (PCPI and PCPIII), and coagulopathy (PAF-ACH). The gene discussed is CXCL8; the disease is achondroplasia.