TP53 and diffuse large B-cell lymphoma: In previous work, we showed that IL-6 upregulated IL-17A by inducing Th17 or Foxp3+ Treg cell differentiation in vitro or in the peripheral blood of DLBCL patients, thereby promoting the growth of k1106 cells or SU-DHL-4 cells by inhibiting irradiation- or rituximab-induce apoptosis through the suppression of p53 expression [17–19].