Compared to subjects in the lowest quartile, subjects in the highest quartiles of transferrin concentrations had a 51% lower risk of dyslipidaemia (OR: 0.49, 95% CI: 0.33–0.71, P < 0.001), while subjects in the highest quartiles of sTfR concentrations had a 32% lower risk of dyslipidaemia (OR: 0.68, 95% CI: 0.46–0.99, P < 0.001) after adjusting for age, gender, BMI, diet and physical activity. The gene discussed is TFRC; the disease is inherited lipid metabolism disorder.