Since ORAI3 is significantly up-regulated in the TNBC cell MES subtype, compared to BLIS and BLIA triple-negative breast cancer cell subtypes, we assessed the effect of two different epithelial to mesenchymal transition (EMT) inducers on the expression of ORAI3 in triple negative, basal-like MDA-MB-468 breast cancer cells. The gene discussed is ORAI3; the disease is breast carcinoma.